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10.1111/j.1365-2982.2011.01796.x Neurogastroenterol

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216 SCFAs, particularly acetate, activate the parasympathetic nervous system, which modulates ghrelin and insulin secretion, 217 forming a complex feedback loop involving the gut, brain, liver and adipose tissue

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And perhaps even more importantlywhen researchers attempted to replicate this spike in hormone levels in subsequent studies, they were never able to do so