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doi: 10.1037/0278-6133.21.6.531 106 MillerA

Subhan et al., 2018)

(Springer Nature Singapore, Singapore), 115

L-cysteine helps support glutathione activity and synthesis

Thus, the excess PyroGlu in a septic patient without an enzymatic deficit in the gamma-glutamyl cycle could be associated with GSH depletion, and therefore excessive oxidative stress and its negative consequences