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B7 variants which act through CD28 with improved activity (and with decreased activity through CTLA-4) will have improved capacity to induce activation of T cells

Improvement of pharmacokinetic profile of TRAIL via trimer-tag enhances its antitumor activity in vivo

From a socio-economic perspective, the application of GO for dye and heavy metal removal is still confined largely to the laboratory stage, with commercial translation only beginning

Conflict of interest The authors report no conflict of interest

Additionally, STK38 interacts with MEKK2 to suppress TLR9 signalling [25], and MEKK2 in turn protects STK38 from calpain-dependent degradation [26]

127,128 Surgery remains the most effective treatment with curative potential, and novel treatments are urgently needed