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Pharmacological characterization To examine whether the potent weight loss observed in vivo after GLP-1MK-801 treatment is attributable to pharmacological synergy between GLP-1 and MK-801 or consequential to altered pharmacokinetic properties of the parent GLP-1 analogue, we designed and synthesized a conjugate comprising an inactive MK-801 surrogate 22 (Supplementary Fig

AhR deficiency exacerbates inflammation in diabetic wounds via impaired mitophagy and cGAS-STING-NLRP3 activation: therapeutic potential of hydrogels loaded with FICZ

[DOI] [PubMed] [Google Scholar] 320.Dispenza C., Sabatino M.A., Ajovalasit A., Ditta L.A., Ragusa M., Purrello M., Costa V., Conigliaro A., Alessandro R