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Privacy: Some individuals prefer the privacy of self-administering B12 injections rather than having them done in a clinical setting

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Standard practice involves rotating injection sites among convenient locations (abdomen, thighs, upper arms) to prevent tissue damage while achieving systemic distribution

Never freeze: Freezing can alter the chemical composition and effectiveness of the injection

Injection technique matters for both compounds but is especially important for semaglutide because the dose must be precise

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