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about one-third is loosely bound to albumin, and two-thirds is unbound

Vitamin B12 plays a vital role in energy production, brain function, and red blood cell formation

This limitation makes conventional vitamin C a poor candidate for therapeutic conditions that demand high absorption vitamin C for sustained or elevated plasma concentrations, such as immune modulation, oxidative stress recovery, and surgical healing

Seven days after in situ injection of DBG scaffold containing indocyanine green (fluorescent substitute for 2-DG) and Cy5.5-labeled BFO, fluorescent signals were still observed in the gel scaffold-based group but not observed in the free drug group (Fig