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Synthesis and bioactivity of novel isoxazole chalcone derivatives on tyrosinase and melanin synthesis in murine B16 cells for the treatment of vitiligo

Thromb Haemost 2022;122:1061-70

The investigators found that 5 of the 34 patients had decreased LVEF

Therefore, butyrate deficiency can be taken as an indirect indicator of impaired intestinal barrier function

125 At the molecular level, aging leads to the downregulation of key transcription factors such as EOMES and T-bet, hindering NK cell maturation

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