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Damage to nerve tissue (peripheral neuropathy), leading to pain, numbness, and weakness in extremities: These can be caused by the vitamins role in the proper functioning of the nervous system

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Vitamin B12 Deficiency and Management During Pregnancy In addition to anaemia, symptoms of vitamin B12 deficiency may include: Fatigue Breathlessness Nervous system symptoms such as numbness, tingling or poor balance Poor concentration or memory Paleness Mood changes, including low mood, anxiety or disrupted sleep Some women are more susceptible to vitamin B12 deficiency than others

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Moreover, elevated plasma Hcy levels have been significantly associated with hypertension (Van Guldener et al., 2003), particularly with systolic blood pressure (SBP) (Shi et al., 2019)