glutathione and colloidal silver Silver Nanoparticles for the Potential Treatment of COVID-19: A Review Probing the interaction of glutathione

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GSH exerts its action as skin whitening agent at various levels of melanogenesis which include the following: [1],[3] Interference with cellular transport of tyrosinase Direct inactivation of the enzyme tyrosinase by binding with the copper-containing active site of the enzyme Mediating the switch mechanism from eumelanin to phaeomelanin production as GSH is the major physiologic reservoir of cysteine and increase in cysteine levels results in switching of eumelanogenesis to pheomelanogenesis [Figure - 1] Quenching of free radicals and peroxides that contribute to tyrosinase activation and melanin formation Modulation of depigmenting abilities of melanocytotoxic agents

However, every individuals skin condition is different, especially during pregnancy

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Importantly, they are essential in critical regulatory processes, including the control of cell specialization, growth, and programmed cell death, among others 27