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As we age, our body's natural production of glutathione decreases and must be replenished through other means

A third problem lies in batch variation and lack of standardization: Plant extracts are compositionally complex, with unstable ratios of active components, making it difficult to establish clear doseresponse relationships

With constant stimulation, these pathways can adapt and reduce responsiveness

Indeed, it is possible as suggested previously 7 that the over-expression of GSTs in homozygous mosquitoes could be protecting Plasmodium parasites against the damaging effects of reactive oxidative species (ROS)