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10.1016/j.expneurol.2020.113415 Exp

Identification of new Shikonin derivatives as STAT3 inhibitors

They found that these enzymes convert tyrosine to fumarate, entering the TCA cycle and generating -ketoglutarate (KG)

A recent investigation stated that combination therapy with NAC and insulin alleviated kidney tissue damage by suppressing ferroptosis in a diabetic beagle dog model induced by STZ and alloxan (ALX)

Stay tuned for more updates on CagriSemas journey toward potential FDA approval, expected no earlier than late 2025, possibly initially for diabetes management

Therefore, IGF-1 delivery strategies for OA treatment should be optimized