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The hidden bulk depicts impaired mitochondrial biology throughout the body, which is multifaceted and may be subdivided into impaired cellular metabolism, cell-specific mitotypes, and mitochondrial behaviours, functions, activities, and features

CBS mRNA induction has been shown to occur in response to the transcription factor Nrf2 [14], in response to several hormones including 1,25-dihydroxyvitamin D3 (the biologically active form of vitamin D) [15], various estrogen receptor ligands [16] and glucocorticoids [17]

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Nevertheless, when kidney injuries are prolonged and overreacted, this reaction becomes pathogenic, ultimately contributing to the emergence of ESRD (Inker et al., 2014)

This delivery method achieves higher serum concentrations more quickly than oral supplementation