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87 Alternatively, hyperexcitable small fiber neurons in PDPN might be more susceptible to bioenergetic failure, increasing distal nerve fiber degeneration

The therapeutic principle of in situ cancer vaccination relies on efficient antigen capture by local APCs, their maturation, and subsequent migration to lymph nodes for T-cell priming

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Follistatin gene therapy improves ambulation in Becker muscular dystrophy

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Although these antibodies were selected on the basis of cytolysis, it is possible that some of their therapeutic effects may be mediated by inhibition of the NADase activity and subsequent NAD boosting effects