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And then there were the Pacific ports, which allowed CJNG to smuggle in vast quantities of precursor chemicals from India and China, and smuggle out the finished product

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These compounds disrupt bacterial membranes, inhibit efflux pumps, downregulate virulence genes, and interfere with quorum-sensing pathways and biofilm maturation, while also attenuating NF-B signaling and pro-inflammatory cytokines

These pathogens often exhibit intrinsic or acquired resistance to antifungal agents, severely limiting treatment options