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Burcelin, R., Knauf, C., Cani, P.D

Due to the high sequence similarity among Ube2e1, Ube2e2, and Ube2e3, we modeled this region based on the Ube2e2 sequence but removed the side chains (Supplementary Fig

Furthermore, TGF- is implicated in various pathological processes associated with PH, including cell proliferation, apoptosis, metabolic dysregulation, mitochondrial dysfunction, inflammation, immunomodulation, ECM remodeling, fibrosis, and EndMT (Fig