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Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter is involved in the induction of ferroptosis

10.1111/bph.15834 112 HuM.HuangJ.ChenL.SunX

Herein, we describe a long-term high-throughput microfluidic liver chip for studying chronic liver diseases compatible with standard laboratory automation technologies

Chronic stress affects hormone levels, including cortisol, which can trigger inflammatory responses in the body

The chemoprotective effect of chlorophyll and its derivatives has been tested in laboratory cell cultures and animals [107, 108]

Four of the identified compounds have mutagenic potential (AMES negative) namely compounds 1 (Methyl methanethiolsulfonate), 13 (S-Methyl methanethiosulphonate), 26 (2-Methoxy-4-vinylphenol), and 29 (2-(hydroxymethyl)-2-nitro-1,3-)