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Description

In general, patients do not feel anything, but some may feel a tinge of tingling

After its discovery in 1980, it gained the attention of different scientists for its antiaging properties

Furthermore, M1 macrophages generate abundant ROS and secrete pro-inflammatory cytokines (e.g., TNF-, IL-6), which propagate lipid peroxidation and impair antioxidant mechanisms in neighboring structural cells (127)