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Cortisol, Stress, and Rosacea Flares Many rosacea patients report worsening during periods of: High stress Poor sleep Emotional strain Burnout Chronic stress may increase: Inflammatory cytokines Histamine release Sympathetic nervous system activation Vascular instability This may intensify flushing and skin sensitivity

[DOI] [PMC free article] [PubMed] [Google Scholar] 39.Gould HP, Rate WR, Harrell RA, Abbasi P, Fillar AL: Effect of poly-L-lactic acid mesh augmentation on cyclic gap formation in transosseous patellar tendon repair: A biomechanical study

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PD-induced mice model was treated with BV2-metformin-loaded PLGA 3 times per week for 34 weeks