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Under normal physiological conditions, uptake of oxLDL by macrophages is probably generally protective, because subsequent efflux of the cholesterol from the macrophages to HDL via reverse cholesterol transport as well as emigration of these macrophages from the arterial wall to lymph nodes serves to minimize the accumulation of cholesterol-laden macrophages in the arterial wall

Author Contributions Substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data: FW, EH, GPC, and AK

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself

Curr Med Res Opin (2023) 39:16177

Furthermore, it has been reported that miR-146a can promote the conversion of Tregs toward a proinflammatory phenotype by enhancing STAT1 activation [76]