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With the rapid development of sequencing technologies, large-scale metagenomic datasets have revealed that site-specific microbiota perform distinct biological functions within defined microenvironments 2,3,4,5 , highlighting the heterogeneity of microbial composition across anatomical sites and underscoring the need for a multi-organ perspective

Intracerebroventricular administration of colchicine produces cognitive impairment associated with oxidative stress in rats

Some have also been efficacious in reducing the generation of uremic toxins (Hida et al., 1996), which are majorly implicated in the progression of CKD and neurodegenerative diseases

The findings indicate that SLC7A11 is most prominently expressed in the brain, followed by the thyroid, stomach, appendix, bladder, and gallbladder, while demonstrating lower expression levels in the kidney, heart, and liver

R Franco, OJ Schoneveld, A Pappa, MI Panayiotidis

doi: 10.1152/ajpheart.00584.2011