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[DOI] [PubMed] [Google Scholar] Luo C, Ding W, Yang C, Zhang W, Liu X, Deng H

doi: 10.1371/journal.pgen.0030023 26 BenucciB.SpinelloZ.CalvaresiV.VivianiV.PerrottaA.FaleriA.et al

Reduced production of peroxided lipids and induction of iron overload were observed in an ACSL4 conditional deletion mouse, conversely, the phenotype was reversed upon overexpression of ACSL4

MELD-3 improvement in HCC patientsincluding within Cluster two where HCC prevalence was 34.9% likely reflects tumour-directed therapies or fluctuations in hepatic reserve unrelated to antioxidant supplementation, and should not be interpreted as evidence of glutathione efficacy

On the other hand, 8-prenylnaringenin has also been found to inhibit aromatase, an enzyme involved in estrogen synthesis, in the laboratoryan effect that could potentially lower E2 levels

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