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The increase in the amount of glycerophosphocholine that we reported would correspond to an increased turnover of phosphatidylcholine consecutive to reduced incorporation of phosphatidylcholines into cell membranes when differentiation was impeded by TNAP inhibition

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suggesting an unappreciated physiologic function

Immunoblotting analysis revealed that phosphorylated ERK, but not total ERK, was upregulated in DLD-1 (KRAS G13D/- ), HCT116 (KRAS G13D/- ), and RKO (BRAF V600E ) cells in comparison to their respective wild-type parent cells (Fig

Binding proteins , opsonins, such as C-reactive protein (CRP), bind to macromolecules released by damaged tissue or infective agents and promote their phagocytosis ( Chapter 38 )