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Concluding Remarks The development of non-cytotoxic anti-CD38 antibodies and small molecules targeting the NADase enzymatic activity of CD38 may present as an important advancement in therapies for cancers and age-related diseases, but many important questions remain about CD38 biology and potential therapeutic uses (see outstanding questions)

[PubMed] [Google Scholar] 26.Sanz-Cuesta T., Escortell-Mayor E., Cura-Gonzalez I., Martin-Fernandez J., Riesgo-Fuertes R., Garrido-Elustondo S., Mario-Surez J.E., lvarez-Villalba M., Gmez-Gascn T., Gonzlez-Garca I., et al

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An G, Acharya C, Feng X, Wen K, Zhong M, Zhang L, et al

For patients interested in AOD-9604 for joint health, the clinical team evaluates joint symptoms, activity level, medical history, and overall health goals to determine candidacy