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GPX4 depletion in mouse embryonic fibroblasts and in neurons causes lipid peroxidation and AIFM1/AIF (apoptosis-inducing factor, mitochondrion-associated 1)-mediated and caspase-independent apoptosis [20]

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This guide works through the existing evidence systematically: the molecular biology that makes BPC-157 plausible, the dosing ranges tested in animal models, the limited but growing human data, and the practical considerations around administration route, cycling, and safety

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