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In addition, emerging evidence from peripheral neuropathy models suggests that DRG neurons can become intrinsically sensitized by chemotherapeutic agents, raising the possibility that altered DRG activity may also influence gut functions independently of local epithelial injury

TABLE 1 Reported skin dysbiosis in psoriasis

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Some studies suggest that there is a sex-specific impact of Se on inflammatory responses, as there is an degree of sexual dimorphism among the distribution of Se in organs of the body that affects Se status and arrangement related to body function [82]