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and Bakken, L.R

10.2164/jandrol.106.002048 104

The gene encoding HGF spans 70 kb on chromosome 7q21.1 is initially in the form of pro-HGF, which is further cleaved by a protease to mature HGF [28]

doi: 10.1161/CIRCRESAHA.110.223545 136

As a complementary strategy to native chemical ligation (NCL) discussed below, STL has certain advantages such as the relatively high abundance of serine and threonine in proteins (12.7%) compared to cysteine (1.5%), no need for N-terminal modification, and compatibility with most of the amino acids at the C-terminus