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Different amyloid subtypes exhibit distinct patterns of deposition both along the proximaldistal axis (horizontal distribution) and within different layers of the intestinal wall (vertical distribution)

Doctors often recommend it as part of long-term therapy for patients who have absorption problems or cannot maintain sufficient B12 through diet alone

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For this reason, the Food and Nutrition Board of the National Academy of Medicine advises that all adults limit their intake of folic acid (supplements and fortification) to 1,000 g (1 mg) daily

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