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149 These cells serve as the primary effector cells of the immune system for pathogen elimination, being activated by IFN- and TNF, and releasing inflammatory cytokines including IL-1, IL-6, IL-12, IL-15, IL-23, TNF, and MIP-1

10.1126/scisignal.2002329 49 KrumanI

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Reverse communication: neighboring cells to endothelium Exosomes derived from various cell types and organs, including macrophages, mesenchymal stem cells, dendritic cells, and perivascular adipose tissue (PVAT), can exacerbate endothelial dysfunction in atherosclerosis [136]

Ghanbari, M., Ahmadnia, H., Moradi, M