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different xenobiotics may induce distinct isoforms of the enzyme

Aliment Pharmacol Ther 60(3):378388 Danpanichkul P et al (2024) Global and regional burden of alcohol-associated liver disease and alcohol use disorder in the elderly

Finally, there is protein oxidation and metabolic obstruction

It's worth noting that -syn functions as a ferrireductase to reduce Fe 3+ to Fe 2+ (Sian-Hulsmann and Riederer 2020)

Mitochondrial pyruvate carrier 1 (MPC1), an inner membrane protein that transfers pyruvate into mitochondria, is differentially expressed in normal and cancer cells, and inhibition of MPC1 expression can prompt a shift towards EMT in cancer cells

doi:10.1155/2021/5529741 11