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HIF-1 is the key transcriptional factor that masterfully regulates endothelial cell biology and angiogenesis, particularly under hypoxic and oxidative stress conditions, by upregulating pro-angiogenic factors, such as VEGF 33

The contents of two active ingredients, sanguinarine and chelerythrine, are 1.5% and 0.075%, respectively

259 Moreover, the loss of the mitochondrial ABC transporter ATM1, which transports intermediates required for FeS cluster formation, exacerbates Cu-induced toxicity

However, although numerous studies of DTP cells have extensively outlined the details of resistance mechanisms, many directions of research into the DTP cells in AML remain to be pursued

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Dextran sodium sulfate colitis murine model: an indispensable tool for advancing our understanding of inflammatory bowel diseases pathogenesis