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With NO, GSH is necessary for the hepatic action of insulin sensitizing agents and plays a crucial role in regulating the redox state of the cell with lipids, glucose, and amino acids

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doi:10.1016/S0140-6736(11)60405-4

doi:10.1042/bj20021234

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Crucially, recent evidence reveals that a ROS-EMT axis creates a physical immune-privileged niche by remodeling the extracellular matrix to exclude T cells, thereby linking oxidative stress directly to immune evasion [112, 113]