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445 The mechanisms by which high-fat diets reduce VAT Tregs remain unclear but may involve pDC-mediated IFN-dependent killing of VAT Tregs, GATA3 downregulation that impairs ST2 Treg differentiation, and disrupted cholesterol homeostasis that limits ST2 Treg clonal expansion

185,186 Chronic traumatic encephalopathy Chronic traumatic encephalopathy (CTE), which results from multiple and repeated mild traumatic injury (experienced for example by professional footballers, hockey players or boxershence its name dementia pugilistica 187