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Clin Infect Dis 55(6):860867

The EGCG-Zn suppositories could be fabricated through a simple and controllable process, as demonstrated by these findings

In mouse models of PD, lycopene exhibits antioxidant properties

Pathways for such a potential interaction are suggested in Figure 7

The fixed organoid cultures were blocked in 5% donkey serum (Millipore, Billerica, MA, USA) + 0.3% Triton-X-100/PBS, incubated overnight in 3% bovine serum albumin (Sigma-Aldrich, St Louis, MO) + PBS with primary antibodies, washed, incubated with Alexa Fluor-conjugated secondary antibodies (Invitrogen, Carlsbad, CA), washed, and stained with DAPI or mounted in VECTASHIELD H-1000

In addition, peptidetreated APP/PS1 mice performed better at the probe test, as evidenced by their higher crossing number (Fig 3B) and longer time spent in the quadrant where the probe used to be compared to PEItreated control transgenics (Fig 3C)