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doi: 10.1002/mpo.10188 231 WuXZhangYPeiZChenSYangXChenYet al

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The small hydrophilic molecules include glucuronic acid, glutathione, sulfate, amino acids, and a methyl group, which are catalyzed by glucuronyl transferases, glutathione transferases, sulfotransferases, amino acid transferases, and N- and O-methyltransferases, respectively [21]

Most safety data comes from mouse studies conducted by Thomas Burris and colleagues at Saint Louis University and later the University of Florida

Our study demonstrates that the DNA-PKcs inhibitor KU-57788 exhibits significant anti-ATC activity both in vitro and in vivo