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In the decades since its discovery, DSIP has been studied across a broader range of research domains beyond sleep physiology

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Analysis of mRNA from the aortas of different groups showed that FOXO4-DRI effectively inhibited the increase of pro-inflammatory factors such as Il-1 , Il-6 , Cxcl15 , and Tnf- (Figure 2B)

Hyaluronic Acid is a polysaccharide that occurs in high amounts in the skin, joints, and eyes, providing lubrication and keeping tissues hydrated

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In previous studies that compared the differentiation capacity of chondrocytes from different passages, the results indicated that cells at early passages usually generated more cartilage matrix than those at late passages upon chondroinduction (Schulze-Tanzil et al., 2002