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When the expression of 44 pro-apoptotic genes was assessed in the postmortem hippocampus, 19 of those genes were significantly upregulated in BD, which was unrelated to the exposure to mood stabilizers [56]

The cells were then washed with cold-PBS three times and analyzed by flow cytometry at 488 nm to detect the expression of P-gp in the tumor cells

For example, THC (3 mg/kg, i.p) administered to WT mice resulted in reduced RhoA/ROCK proteins compared to vehicle exposed mice, leading to increased myelin-related proteins and enhanced OPC differentiation (Snchez-de la Torre et al., 2022)

These studies should consider potential off-target effects, the impact on milk quality and yield, and overall animal health and welfare

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A dual-targeting photosensitizer for simultaneous mitochondrial and lysosomal disruption in cancer and antibacterial photodynamic therapy