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Voclosporin, a novel calcineurin inhibitor, was investigated in a phase II trial for lupus nephritis as a combination therapy with mycophenolate mofetil (AURA trial)

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Silymarin downregulates MPO/MDA [534] and blocks the IL-6/STAT3 [535]-cell division cycle 25C (Cdc25C)/(cyclin-dependent kinase 1) CDK1 [536] proliferation signal