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Soluble uric acid activates the NLRP3 inflammasome

Another study reported that treatment with particulate -glucan substantially reduces MDSCs in tumor-bearing mice but increases the infiltrated M and DCs, thus inducing Th1 and CTL responses and suppressing the immunosuppressive effects of regulatory T cells (260)

The benzyl alcohol stops bacterial growth, which is what lets a reconstituted vial be used across multiple doses over several weeks in the fridge

10.1126/science.1261821 Science 30 ChenX.MarreroH.FreedmanJ

These include paracellular and transcellular passive diffusion [4], carrier-mediated transcytosis [5, 6], and receptor-mediated transcytosis [5, 6] (Fig