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In the context of atherosclerosis, a comprehensive systems-level analysis of EC metabolic reprogramming provides an important avenue for developing targeted therapeutic interventions aimed at mitigating age-related vascular pathologies [3]

Lemos-Filho LB, Mikkelsen ME, Martin GS, Dabbagh O, Adesanya A, Gentile N, Esper A, Gajic O, Gong MN

"Synthesis and cytotoxic profile of 3,4-methylenedioxymethamphetamine ("ecstasy") and its metabolites on undifferentiated PC12 cells: A putative structure-toxicity relationship" (PDF)

Young adult male rats metabolize drugs much faster than mature female rats or prepubertal male rats

Metabolic pathway enrichment analysis demonstrated that five pathways showed significant associations with metabolic disparities between the two groups