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BeckAFHuangBKercsmarCMGuilbertTWMcLindenDJLierlMBet al

S also interacts and inhibits the activity of TOM20 (Di Maio et al., 2016), which impairs the redistribution of Sirt3 into mitochondria from the cytoplasm and increases mitochondrial stress (Motyl et al., 2018)

Bol GM, Vesuna F, Xie M, Zeng J, Aziz K, Gandhi N, et al

Besides the colon cancer cells, the elevation of p70S6K1 phosphorylation is also observed in breast cancer MCF7 cells treated with an IGF-1R inhibitor, OSI-906

Crack PJ, Taylor JM, Flentjar NJ, de Haan J, Hertzog P, Iannello RC et al

Additional redox-active selenoproteins include (i) Msr, where the ratio of the reduced/oxidised form (of methionine) communicates cellular redox status [50], (ii) selenoprotein P that acts principally as a Se carrier but also undergoes redox reactions [51,52,53,54] and (iii) deiodinases that are oxidoreductase enzymes crucial for thyroid function [55]