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Some people who take PPI medicines, including NEXIUM, may develop certain types of lupus erythematosus or have worsening of the lupus they already have

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Sdu Journal of Health Sciences 10:4 Fernando RA, Fennell TR, Watson SL, Silinski MAR, Blake JC, Robinson VG, Waidyanatha S (2022) Development and validation of an analytical method for quantitation of Alpha-pinene oxide in rodent blood and mammary glands by GC-MS

While electrostatic repulsion from phosphate group addition is known to disrupt protein-nucleotide interactions 103 , our data indicates that S114 phosphorylation does not alter binding by the nuclear export receptor, XPO-1

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It should be noted that the baseline vitamin B12 levels in this cohort were significantly higher than in the KEMU cohort ( p = 0.006), which may explain the faster exceeding of the vitamin B12 threshold