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In 2022, an estimated 10.6 million people developed TB, with a high prevalence in South-East Asia (notably India, Indonesia, China, the Philippines, Pakistan, and Bangladesh) and Africa (including Nigeria and the Democratic Republic of the Congo)

Clinical trial group members Afrnio Ferreira Evangelista, Camila Oliveira Valente, Carolina Th Macedo, Cassio Santana Meira, Crislaine Gomes da Silva, Danielle Devequi Gomes Nunes, Emanuelle de Souza Santos, Katharine Valria Saraiva Hodel, Leticia de Alencar Pereira Rodrigues, Patrcia Kauanna Fonseca Damasceno, Rodrigo Souza Conceio, and Vincius Pinto Costa Rocha (Institute of Health Technologies ITSSENAI CIMATEC)

Lactate accumulation may not accurately reflect glycolytic activity, as other pathways (e.g., glutamine and pentose phosphate pathways) also contribute to lactate production

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Central mechanisms of stress integration: Hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness

Koh Y-C, Tsai Y-W, Lee P-S, et al