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RNA Sequencing Identifies Gene Regulatory Networks Controlling Extracellular Matrix Synthesis in Intervertebral Disk Tissues

As we will discuss below, glucoraphanin-rich preparations with active myrosinase enzyme are often used today in clinical trials as glucoraphanin precursor is more stable than sulforaphane (Yagishita et al., 2019) (Table 1)

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Fibroblast Proliferation and Collagen Synthesis In the context of connective tissue repair, fibroblasts are critical for producing and remodeling the extracellular matrix, primarily through collagen synthesis