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Common clinical drivers include: Vitamin B12 deficiency Folate deficiency Chronic liver disease Alcohol use disorder Medications (e.g., methotrexate) Bone marrow disorders Chronic inflammatory disease Hypothyroidism Key ICD-10 principle: Cell size is a laboratory observation

The use of AOD 9604 and Tirzepatide should always be monitored to ensure safety and to align with post treatment goals

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A review of 18 different studies in patients with NCGS found iron deficiency was present in 15-34% of patients

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If vitamin B12 deficiency is not treated with a vitamin B12 supplement, then anemia, intestinal problems, and irreversible nerve damage may occur