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However, their results have also demonstrated increased oxidation of lipid substrates, indicating elevated oxidative stress levels (Lastres-Becker et al., 2022), which suggests that the NRF2-mediated antioxidant machinery may be activated but to an insufficient degree in ALS

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Free NRF2 moves into the nucleus and binds to antioxidant response elements located in the promoters of genes encoding the GSH redox buffering system

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Borrelia and Chlamydia can form mixed biofilms in infected human skin tissues