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Without GSH, the immune system cannot function, and the central and peripheral nervous systems become aberrant and then cease to function

In addition, inflammation and microbial infections exacerbate hypoxia, creating a vicious cycle that further hinders wound healing [69]

More interestingly, injection of senescent cancer cells or dendritic cells activated by senescent cells in mice protects from tumor engraftment, induces significant tumor regression, and potentiates immunotherapies