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Methods: Among 102 patients who were enrolled in the Japanese phase 3 clinical trial of sofosbuvir and velpatasvir (SOF/VEL) with or without ribavirin (RBV) treatment to decompensated cirrhotic patients with HCV, 99 patients who agreed to a long-term follow up study were included in this study

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Collectively, PCBPs can regulate the cellular distribution of labile iron by depositing it into the cellular iron reservoir ferritin and/or by directing it to the site of utilization as an inorganic cofactor for cytosolic non-heme iron enzymes

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