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When dissolved in a solution, that nicotine can enter the body directly through the skin

But the image invites one to think that it might become so

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For example, the sample sizes of the published studies are small, and further evaluation in larger populations is required to establish the evidence for potential approval, oversight, and regulation by regulatory agencies such as FDA and EMA (86)

A comprehensive literature search from the year 2000 was conducted through PUBMED using the search terms anti-inflammatory and nicotine, anti-inflammation and nicotine, pro-inflammatory and nicotine, inflammation and nicotine, and pro-inflammation and nicotine

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