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Furthermore, the researchers found that the expression of G1 and G2 resulted in a consistent increase in the quantity of cytoplasmic Ca 2+ in cell-based models

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These results imply not only that the CAR-HSC complex could completely breakup their interactions when Ca ions are more than 10 times the CAR molecules penetrating SC layers, but also that the dominant factor for such disruption is the affinity between CAR and Ca ions

KaplanMeier survival curves were generated to compare outcomes between high and low gene expression groups, with statistical significance evaluated using the log-rank test

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