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doi: 10.1126/scisignal.abj8393 43 BhatSMBadigerVAVasishtaSChakrabortyJPrasadSGhoshSet al

The stability of the radical arises from the steric hindrance around the first-order divalent nitrogen atom and the "pushpull" effect between the second-order diphenylamino group as an electron donor and the picryl group as an electron acceptor

14:e0221103

No specific human trials in optic neuritis

Data availability All data are available within the paper, extended data, source data files and supplementary files

In this review, we will revisit the traditional roles of NADPH in inflammatory and anti-inflammatory pathways and highlight studies that reveal the competition for its consumption between these opposing pathways as a way to regulate inflammation in myeloid cells